质量标准：【产品介绍】Bcl-x, a member of the Bcl-2 protein
family, inhibits cell death, o r apoptosis (1). Bcl-x
is expressed as two isomeric f o r ms, Bcl-xL a n d
Bcl-xS, a n d is typically present in the cytosol
in association with the mitochondrial membrane. Bcl-xL
f o r ms heterodimers with various proteins, including
Bax, Bak a n d Bcl-2 (2). It has been found that eterodimerization with Bax does not seem to be required
f o r anti-apoptotic activity (3). Since Bcl-xL can
f o r m an ion channel in synthetic lipid membranes,
there is a strong possibility that this property plays
a role in heterodimerization-independent cell survival
(4). The Bcl-X(S) isof o r m promotes apoptosis.
WB: 1:1,000
IHC: 1:50 - 1:100
ICC: 1:100
Flow Cytometry: 1:50
IP: 1:10
A. Western blot analysis of K562 cell lysate
using anti-Bcl-x RabMAb (catalog #1018-1), 1:1,000 dilution.
B. Immunohistochemical analysis of human
paraffin-embedded prostate carcinoma tissue using
anti-Bcl-x RabMAb (catalog #1018-1).
C. Flow cytometric analysis of permeabilized K562
cells using anti-Bcl-x RabMAb (red) (catalog #1018-1)
o r a Rabbit IgG (negative) (green).
沪公网安备 31012002003055号