质量标准:【产品介绍】CDK7 is a member of the cyclin-dependent
protein kinase (CDK) family. CDK family members are
highly similar to the products of Saccharomyces
cerevisiae cdc28, and Schizosaccharomyces pombe cdc2,
and are known to be important regulators of cell
cycle progression. CDK7 forms a trimeric complex with
cyclin H and MAT1, which functions as a
Cdk-activating kinase (CAK). It is an essential component
of the transcription factor TFIIH, that is involved
in transcription initiation and DNA repair. CDK7 is
thought to serve as a direct link between the regulation
of transcription and the cell cycle (1).
Recommended Applications
WB
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
Species Reactivity *
Human
*Species cross-reactivity is based on WB analysis.
Products Data
Western blot analysis on (A) MCF-7, (B) A431, and
(C) HeLa cell lysates using anti-CDK7 RabMAb (cat. #5139-1).
Specificity
A recombinant protein fragment corresponding to residues
in human CDK7 was used as an immunogen.
贮存:Storage Condition and Buffer
Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt