质量标准:【产品介绍】Emtk/Itk/Tsk is a member of the Tec family
of Protein Tyrosine Kinase (PTK) expressed in T, NK,
a n d mast cells (1). Structurally, Emtk/Itk/Tsk possesses
a tyrosine kinase (TK), a pleckstrin homology (PH) a n d
a TEC homology domain. It also contains both SRC homology
2 (SH2) a n d a SRC homology 3 (SH3) domains (2). It
lacks as well the amino-terminal myristylation signal
a n d the negative aut o r egulat o r y phosph o r
ylation site present in all members of the Src family
of PTKs (3). Additionally, the Src tyrosine kinase LCK
is required f o r Emtk/Itk/Tsk activation a n d
recruitment by CD28 (4).
WB: 1:1,000
IHC: 1:50-100
A. Western blot analysis of anti-Emtk/Itk/Tsk
(C-term) Rabbit Polyclonal (cat. # 1581-1),
dilution 1:1,000. A-K562 B-A431
B. Immunohistochemical analysis of paraffin-embedded n
o r mal lymph node using anti-Emtk/Itk/Tsk (C-term)
Rabbit Polyclonal (cat. # 1581-1).