质量标准：【产品介绍】Erzin, a member of the Ezrin, Radixin,
Moesin (ERM) family, is a linker protein located
between cell surface recept o r s, adhesion molecules,
a n d actin cytoskeleton (1-2). Ezrin activity is
regulated by intramolecular interactions between
N- a n d C-terminal ERM association domains (3). Phosph
o r ylation at threonine 567 is a critical regulat o r
of ezrin function allowing the active protein to link
target molecules to the actin cytoskeleton (4).
Erzin tyrosine phosph o r ylation can also be induced
by EGF, PDGF a n d HGF stimulation. Erzin interacts
with PI3-K protein kinase A a n d Rho (5).
WB: 1:5,000-50,000
IHC: 100-250
ICC: 50-100
Flow Cytometry: 1:80
IP: 1:50
A. Western blot analysis on Hela cell lysate
using anti-Ezrin RabMAb (cat. # 1729-1), dilution 1: 50,000
B. Immunohistochemical analysis of paraffin-embedded
human colon carcinoma using anti-Ezrin RabMAb
(cat. # 1729-1).
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