质量标准:【产品介绍】The growth fact o r bound protein 2 (GRB2) is
a 25 kDa cytosolic protein that contains one src
homology (SH2) domain a n d two SH3 domains (1).
GRB2 associates with Tyrosine phosph o r ylated EGFRs
a n d PDGFRs via its SH2 domain. GRB2 also plays a
crucial role in two separate insulin pathways leading
from the insulin recept o r to the Ras protein
thus affecting mitogenic signaling (2). Additionally GBR2,
a bifunctional adapt o r protein, recruits Sos f o r
Ras activation a n d subsequent signal transmission (3).
WB: 1:5,000-10,000
IHC: 1:100-250
ICC: 1:50-100
IP: 1:50
A. Western blot analysis on 293 cell lysate using
anti-GRB2 (C-term) RabMAb (catalog #1517-1),
dilution 1:10,000.
B. Immunohistochemical staining of paraffin-embedded
human ovarian carcinoma using anti- GRB2 (C-term)
RabMAb (catalog #1517-1).
C. Immunoflu o r escent staining of HeLa cells
using anti-GRB2 (C-term) RabMAb (catalog #1517-1).