质量标准:【产品介绍】HP1 alpha is a highly conserved
nonhistone protein, which is a member of the
heterochromatin protein family. It is enriched in
the heterochromatin and associated with centromeres.
HP1 alpha has a single N-terminal chromodomain that can
bind to histone proteins via methylated lysine residues
and a C-terminal chromo shadow-domain (CSD) that
is responsible for the homodimerization and interaction
with a number of chromatin-associated nonhistone
proteins. It is involved in the formation of a
functional kinetochore through interaction with
essential kinetochore proteins (1).
Recommended Applications
ICC
Applications and Recommended Dilution Factors
ICC: 1:100
Species Reactivity
Human
Products Data
Immunofluorescent analysis of HeLa cells using HP1
alpha RabMAb (DyLight® 488 conjugate, cat.# 4577-1)
(green) and dapi (blue).
Specificity
A synthetic peptide corresponding to residues in human
HP1 alpha was used as an immunogen.