Human IgD (IGHD)

分子式：

分子量：

别名：
IGHD antibody, FLJ00382 antibody, FLJ46727 antibody, MGC29633 antibody, Ig delta chain C region antibody, antibody

产品订购：

品名	规格	包装	单价	货期
Human IgD (IGHD)		100ul	询价	现货

性状：
【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human
【克隆 ID】EPR6146
【用途】WB , IHC
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】75kDa

质量标准：
【产品介绍】Immunoglobulin (Ig) molecules consist of
two chains, one heavy chain and one light chain,
each consisting of a variable and a constant region. An
IgD molecule contains thus a delta heavy chain combined
with either a kappa or lambda light chain. It is the
major antigen receptor isotype on the surface of
most peripheral B-cells, where it is coexpressed with
IgM (1). Secreted IgD might enhance immune protection
by regulating B cell homeostasis and activation (2).
After the antigen binds to the B-cell receptor, secreted
IgD is shut off. IgD is a potent inducer of TNF, IL1B,
and IL1RN. IgD also induces release of IL6, IL10, and
LIF from peripheral blood mononuclear cells. Monocytes
seem to be the main producers of cytokines in vitro in
the presence of IgD (1).

Recommended Applications
WB, IHC
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IHC: 1:1,000 - 2,000
Species Reactivity *
Human
*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on human tonsil lysate
using anti-Human IgD (IGHD) RabMAb (cat. #5231-1).

Immunohistochemical analysis of paraffin-embedded
human tonsil tissue using anti-Human IgD (IGHD) RabMAb
(cat. #5231-1).

Specificity
A synthetic peptide corresponding to residues in human
IgD (IGHD) was used as an immunogen.

贮存：
Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt