质量标准:【产品介绍】IL-7 is a cytokine important for B and T
cell development. This cytokine and the hepatocyte
growth factor (HGF) form a heterodimer that functions as
a pre-pro-B cell growth-stimulating factor. This cytokine
is found to be a cofactor for V(D)J rearrangement of the
T cell receptor beta (TCRB) during early T cell
development. This cytokine can be produced locally
by intestinal epithelial and epithelial goblet cells,
and may serve as a regulatory factor for intestinal
mucosal lymphocytes. Knockout studies in mice suggested
that IL-7 plays an essential role in lymphoid cell
survival (1).
Recommended Applications
WB
Applications and Recommended Dilution Factors
WB: 1:10,000 - 50,000 (5 ng)
Species Reactivity *
Human
*Species cross-reactivity is based on WB analysis.
Products Data
Western blot analysis on 5 ng of IL-7 recombinant
protein using anti- IL-7 RabMAb (cat. #5412-1).
Specificity
A synthetic peptide corresponding to residues on
the C-terminus in human IL-7 was used as an immunogen.