Fumitremorgin C
MDL:
MFCD08702652
Molecular Formula:
C22H25N3O3
Molecular Weight:
379.45
Alias:
Tryptoquivaline
FTC
Product order:
Name |
Specifications |
Packing |
Price |
Delivery |
Fumitremorgin C |
98% |
0.25mg |
RMB 2160.4 |
Consulting service |
Character:
Fumitremorgin C is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotecan in S1-M1-3.2 colon carcinoma cells. Fumitremorgin C reverses multidrug resistance in cells overexpressing BCRP but not P-glycoprotein (ABCB1) or MRP1 (ABCC1).
Fumitremorgin C is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotecan in S1-M1-3.2 colon carcinoma cells. Fumitremorgin C reverses multidrug resistance in cells overexpressing BCRP but not P-glycoprotein (ABCB1) or MRP1 (ABCC1).
Storage:
储存温度:−20°C
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