Quality Standard:【产品介绍】ABCG5 is a member of the superfamily
of ATP-binding cassette (ABC) transporters. ABC
proteins transport various molecules across extra- and
intra-cellular membranes. ABC proteins are divided
into seven distinct subfamilies (ABC1, MDR/TAP, MRP,
ALD, OABP, GCN20, White). ABCG5 is a member of the
White subfamily. It functions as a half-transporter to
limit intestinal absorption and promote biliary excretion
of sterols. ABCG5 is expressed in a tissue-specific
manner in the liver, colon, and intestine. Mutations in
this protein may contribute to sterol accumulation
and atheroschlerosis, and they have been observed
in patients with sitosterolemia (1).
Recommended Applications
WB
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
Species Reactivity *
Human
*Species cross-reactivity is based on WB analysis.
Specificity
A synthetic peptide corresponding to residues in human ABCG5 was used as an immunogen.
Storage:Storage Condition and Buffer
Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from
date of receipt