Quality Standard：【产品介绍】Autophagy is a process of bulk degradation
of cytoplasmic components by the lysosome/vacuole a n d
has a significant relationship to several
neurodegenerative dis o r ders a n d myopathies in
mammals (1). Apg7 (Atg7) is a unique E1 enzyme which
is essential f o r both the Apg12p- a n d
Apg8p-modification systems, a n d plays indispensable
roles in autophagy (2). A new molecular pathway has
been defined in which activation of the recept
o r -interacting protein (a serine-threonine kinase)
a n d Jun amino-terminal kinase induced cell death with
the m o r phology of autophagy. Autophagic death
required Atg7 a n d beclin 1 a n d was induced by
caspase-8 inhibition (3).
WB: 1:500,000
IHC: 1:100 250
ICC: 1:250 500
Flow Cytometry: 1:95
IP: 1:50
A. Western blot analysis on Jurkat cell lysate
using anti-Atg7 RabMAb (cat. # 2054-1), dilution 1:500,000.
B. Immunohistochemical analysis of paraffin-embedded
human liver using anti-Atg7 RabMAb (cat. #2054-1).
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