Quality Standard:【产品介绍】Bcl-2 related protein A1; also known as Bcl2A1
a n d Bfl1, is an anti-apoptotic Bcl-2 family
member preferentially expressed in hematopoietic
a n d endothelial cells (1). Bfl1 is involved in a
variety of cellular activities such as
embryonic development, homeostatis a n d tum o r
igenesis. Expression of Bfl1 is stimulated by NF-kB
in response to inflammat o r y stimuli a n d is
up-regulated by TNF-alpha, IL1-beta, IGF1, GMC-SF, CD40
a n d ph o r bol ester (2-3). Blf1 has also been shown
to reduce the release of pro-apoptotic cytochrome c from
the mitochondria, block caspase activation a n d
suppress apoptosis induced by p53 (4-5).
WB: 1:500
IHC: 1:50
ICC: 1:100-250
Flow Cytometry: 1:30
A. Western blot analysis on Raji cell lysate using
anti- Bcl-2-related protein A1 (N-term) RabMAb
(cat. # 1639-1), dilution 1:500.
B. Immunohistochemical analysis of paraffin-embedded
human adenocarcinoma using anti-Bcl-2-related protein
A1 (N-term)RabMAb (cat. # 1639-1).
C. Immunoflu o r escent staining of HeLa cells
using anti-Bcl-2-related protein A1 (N-term) RabMAb
(cat. # 1639-1).