Quality Standard：【产品介绍】c-Rel is a member of the nuclear factor
kB (NF-kB) transcription factor family. The NF-kB family
of dimeric transcription factors consists of four
other mammalian members, RelA (p65), RelB, NF-kB1
(p105/p50) and NFkB2 (p100/p52) and is involved in
many biological processes such as inflammation,
immunity, differentiation, cell growth, tumorigenesis
and apoptosis. c-Rel is a proto-oncogene that may play
a role in differentiation and lymphopoiesis. c-Rel
form different dimer combinations that act
as transcriptional activators of repressors (1).
Findings indicate that RelA and c-Rel control
the development of the epidermis and associated
appendages during embryogenesis; they regulate
epidermal homeostasis in a postnatal environment through
the suppression of innate immune-mediated inflammation (2).
Recommended Applications
WB, IP
Applications and Recommended Dilution Factors
WB: 1:10,000 - 50,000
IP: 1:10 - 100
Species Reactivity
Human
Products Data
Western blot analysis on (A) Daudi and (B)HuT-78
cell lysates using anti-c-rel RabMAb (cat. #2793-1).
Specificity
A synthetic peptide corresponding to residues in human
c-Rel was used as an immunogen.
Storage：Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt.
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