Rabbit Monoclonal Antibody

Molecular Formula：

Molecular Weight：

Alias：
CST3 antibody, ARMD11 antibody, MGC117328 antibody, Cystatin-C antibody, Cystatin-3 antibody, Gamma-trace antibody, Neuroendocrine basic polypeptide antibody, Post-gamma-globulin antibody

Product order：

Name	Specifications	Packing	Price	Delivery
Rabbit Monoclonal Antibody		100ul	Inquiry	现货

Character：
【反应特异性】Human
【克隆 ID】EPR4502
【用途】WB , IHC , ICC , IP
【抗原分子量】13kDa

Quality Standard：
【产品介绍】The cystatin superfamily encompasses
proteins that contain multiple cystatin-like sequences.
Some of the members are active cysteine protease
inhibitors, while others have lost or perhaps never
acquired this inhibitory activity. There are
three inhibitory families in the superfamily, including
the type 1 cystatins (stefins), type 2 cystatins and
the kininogens. The type 2 cystatin proteins are a class
of cysteine proteinase inhibitors found in a variety
of human fluids and secretions, where they appear to
provide protective functions. Cystatin C is the
most abundant extracellular inhibitor of cysteine
proteases, which is found in high concentrations
in biological fluids and is expressed in virtually
all organs of the body. A mutation in Cystatin C has
been associated with amyloid angiopathy. Expression of
this protein in vascular wall smooth muscle cells
is severely reduced in both atherosclerotic and
aneurysmal aortic lesions, establishing its role in
vascular disease (1).

Recommended Applications

WB, IHC, ICC, IP
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:100 - 250
IP: 1:10 - 100
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis

Products Data

Western blot analysis on (A) human testis, (B) human
brain, (C) PC-3, and (D) HepG2 lysates using
anti-Cystatin C RabMAb (cat. #3805-1).

Immunohistochemical analysis of paraffin-embedded
human ovarian tissue using anti-Cystatin C RabMAb
(cat.# 3805-1).

Specificity

A recombinant protein fragment corresponding to amino
acids 27-146 of human Cystatin C was used as an immunogen.

Storage：
Storage Condition and Buffer

Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt.