Quality Standard:【产品介绍】Death associated protein 1 (DAP-1) is a
15-kDa protein that functions as a positive mediat o r
of cell death initiated by interferon (IFN-) gamma
(1,2). DAP-1 is proline rich a n d possesses one SH3
binding motif, as well as several consensus protein
kinase phosph o r ylation sites (1). It is localized to
the cytoplasm, but the detailed mechanism of
its pro-apoptotic function is unclear. DAP-1 a n d
DAP kinase, a unique, 160-kDa calmodulin-
dependent serine/threonine kinase, are both unique c
a n d idates f o r positive mediat o r s of programmed
cell death induced by IFN-gamma (3).
WB: 1:10,000
IHC: 1:100-1:250
ICC: 1:250
IP: 1:50
A. Western blot analysis on NIH3T3 cell lysate
using anti-DAP-1 RabMAb (catalog #1059-1), dilution 1:10,000.
B. Immunohistochemical analysis of paraffin-embedded
human stomach carcinoma using anti-DAP-1 RabMAb
(catalog #1059-1).
C. Immunoflu o r escent analysis of HeLa cells
using anti-DAP-1 RabMAb (catalog #1059-1).