Quality Standard:【产品介绍】Daxx is a nuclear protein that has been found
to the enhance Fas-mediated apoptosis a n d activate the
JNK pathway (1). Apoptosis signal-regulating kinase 1
(ASK1) controls the dual function of Daxx as
a transcriptional repress o r in the nucleus a n d as
a proapoptotic signal mediat o r in the cytoplasm (2).
Daxx associates with various proteins,
including promyelocytic leukemia protein (PML) a n d
heat shock protein 27, lending significance to their
roles in tum o r suppression a n d Daxx-mediated
apoptosis (3,4).
WB: 1:5,000
IHC: 1:50 - 1:100
ICC: 1:50
Flow Cytometry: 1:20
A. Western blot analysis on HeLa cell lysate using
anti-Daxx RabMAb (cat. #1094-1), 1:5,000 dilution.
B. Immunohistochemical analysis of paraffin-embedded
human stomach adenocarcinoma using anti-Daxx RabMAb
(cat. #1094-1).