HLA-B

Molecular Formula：

Molecular Weight：

Alias：
HLA-B antibody, AS antibody, Bw-45 antibody, Bw-48 antibody, Bw-56 antibody, HLA-B-5601 antibody, HLA-B-6701 antibody, HLA-B27 antibody, HLA-B73 antibody, HLAB antibody, MGC111087 antibody, SPDA1 antibody, HLA class I histocompatibility antigen, B-7 alpha

Product order：

Name	Specifications	Packing	Price	Delivery
HLA-B		100ul	Inquiry	现货

Character：
【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human
【克隆 ID】EP2624
【用途】WB , IHC , ICC , IP
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】44kDa

Quality Standard：
【产品介绍】HLA-B belongs to the HLA class I heavy
chain paralogues. This class I molecule is a
heterodimer consisting of a heavy chain and a light
chain (beta-2 microglobulin). The heavy chain is anchored
in the membrane. Class I molecules play a central role
in the immune system by presenting peptides derived from
the endoplasmic reticulum lumen. They are expressed
in nearly all cells. The heavy chain is approximately
45 kDa and its gene contains 8 exons. Exon 1 encodes
the leader peptide; exon 2 and 3 encode the alpha1
and alpha2 domains, which both bind the peptide; exon
4 encodes the alpha3 domain; exon 5 encodes
the transmembrane region; and exons 6 and 7 encode
the cytoplasmic tail. Polymorphisms within exon 2 and exon
3 are responsible for the peptide binding specificity
of each class I molecule. Typing for these polymorphisms
is routinely done for bone marrow and
kidney transplantation. Hundreds of HLA-B alleles have
been described.

Recommended Applications
WB, IHC, ICC, IP
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:250 - 500
IP: 1:10 - 100
Species Reactivity
Human

Products Data

Western blot analysis on (A) Ramos, (B) HL-60, (C)
Jurkat, and (D) TF-1 cell lysates using anti-HLA-B
RabMAb (cat. # 2389-1).

Immunohistochemical staining of paraffin-embedded
human tonsils using anti-HLA-B RabMAb (cat. #2389-1).

Specificity
A synthetic peptide corresponding to residues in human
HLA-B was used as an immunogen.

Storage：
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt.