HNF4A

Molecular Formula：

Molecular Weight：

Alias：
HNF4A antibody, FLJ39654 antibody, HNF4 antibody, HNF4a7 antibody, HNF4a8 antibody, HNF4a9 antibody, HNF4alpha antibody, MODY antibody, MODY1 antibody, NR2A1 antibody, NR2A21 antibody, TCF antibody, TCF14 antibody, Hepatocyte nuclear factor 4-alpha antibo

Product order：

Name	Specifications	Packing	Price	Delivery
HNF4A		100ul	Inquiry	现货

Character：
【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human
【克隆 ID】EPR3648
【用途】WB , IHC , ICC , FC , IP 【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】52kDa

Quality Standard：
【产品介绍】HNF4 (Hepatocyte Nuclear Factor 4) is a
nuclear receptor protein belonging to the steroid
hormone receptor superfamily. HNF4 is commonly expressed
in the liver and plays a critical role in liver
development by establishing and maintaining
hepatocyte differentiation (1). In human, two isoforms
of HNF4 exists, alpha and gamma. HNF4 alpha
is transcriptionally controlled transcription factor,
which binds to DNA sites required for the transcription
of alpha 1- antitrypsin, Apo CIII, transthyretin genes,
and HNF1 alpha (2). HNF4 alpha interacts with PGC-1
to activate gluconeogenesis, leading to
lipoprotein metabolism regulation (3). HNF4 alpha
defects are known to cause type I diabetes (4).

Recommended Applications
WB, IHC, ICC, IP, FC
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:100 - 250
IP: 1:10 - 100
FC: 1:10 - 100
Species Reactivity
Human

Products Data

Western blot analysis on (A) HepG2, (B) A549 and (C)
SW480 cell lysates using anti-HNF4 Alpha RabMAb
(cat. #2803-1).

Immunohistochemical analysis of paraffin-embedded
human colon tissue using anti-HNF alpha RabMAb
(cat. #2803-1).

Immunohistochemical analysis of paraffin-embedded
human kidney tissue using anti-HNF alpha RabMAb
(cat. #2803-1).

Immunofluorescent staining of HepG2 cells using
anti-HNF4 alpha RabMAb (cat. #2803-1).

Specificity
A synthetic peptide corresponding to residues in human
HNF4 Alpha was used as an immunogen.

Storage：
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt.