Ku80 (XRCC5)

Molecular Formula：

Molecular Weight：

Alias：
XRCC5 antibody, FLJ39089 antibody, KARP-1 antibody, KARP1 antibody, KU80 antibody, KUB2 antibody, Ku86 antibody, NFIV antibody, X-ray repair cross-complementing protein 5 antibody, X-ray repair complementing defective repair in Chinese hamster cells 5 (do

Product order：

Name	Specifications	Packing	Price	Delivery
Ku80 (XRCC5)		100ul	Inquiry	现货

Character：
【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human
【克隆 ID】EPR3468
【用途】WB , IHC , ICC , IP
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】86kDa

Quality Standard：
【产品介绍】The Ku antigen is a DNA-associated
nuclear protein originally recognized by the sera
of patients with autoimmune diseases (1). It plays a
key role in multiple nuclear processes, such as DNA
repair, chromosome maintenance, transcription
regulation, and V(D)J recombination (2). The Ku protein
is composed of 70 and 80 kDa subunits (Ku70 and
Ku80, respectively) and contributes to genomic
integrity through its ability to bind DNA
double-strand breaks and facilitate repair by
the non-homologous end-joining pathway (3). When bound
to DNA, the Ku 70/80 heterodimer enhances the
kinase activity of the catalytic subunit of
the DNA-dependent protein kinase, DNA-PKcs (4).

Recommended Applications
WB, IHC, ICC, IP
Applications and Recommended Dilution Factors
WB: 1:10,000 - 20,000
IHC: 1:250 - 500
ICC: 1:500 - 1000
IP: 1:50
Species Reactivity *
Human
*Cross reactivity determined by western blot only.

Products Data

A. Western blot analysis on (A) A549 treated with FBS
(B) HeLa (C) HepG2 (D) MCF-7 cell lysates using
anti-Ku80 RabMAb (cat. #2620-1), dilution 1:50,000.

B. Immunohistochemical analysis of paraffin-embedded
human tonsil tissue using anti-Ku80 RabMAb (cat.# 2620-1).

C. Immunofluorescent staining of HeLa cells using
anti-Ku80 RabMAb (cat. #2620-1).

Specificity
A synthetic peptide corresponding to residues in human
Ku80 was used as an immunogen.

Storage：
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt.