Quality Standard:【产品介绍】LMO2 (LIM-only protein 2, RBNT2), a member
of the LIM-only class of transcriptional co-regulators
that consist of two closely spaced cysteine-rich LIM
domains has distinct functions in erythropoiesis and
in T-cell leukemogenesis. These diverse functions of
LMO2 are presumed to be accomplished through
physical interaction with different protein partners
that bind the LIM domains of LMO2 (1). It is also
required for early stages of hematopoiesis, and the
LMO2 master gene encodes a protein that has a central
and crucial role in the hematopoietic development (2).
LMO2 has been identified as a novel oncogene
associated with carcinogenesis and prognosis in
several malignant tumors (3)
Recommended Applications
WB, IP, FC
Applications and Recommended Dilution Factors
WB: 1:1000 - 10,000
IP: 1:100 - 500
FC: 1:100 - 500
Species Reactivity
Human, Mouse, Rat
Products Data
Western blot analysis on (A) Raji cell lysate and (B)
Fetal kidney lysate using anti-LMO2 RabMAb (cat. #2668-1).
Specificity
A synthetic peptide corresponding to residues in human
LMO2 was used as an immunogen.