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Folinic acid calcium salt hydrate

Cas:
1492-18-8
Molecular Structure:
Molecular Formula:
C20H21CaN7O7 ·xH2O
Molecular Weight:
511.50
Alias:
N-[4-[(2-氨基-5-甲酰基-1,4,5,6,7,8,-六氢-4-氧代-6-蝶啶基)甲基]氨基]苯甲酰基-L-谷氨酸钙盐五水合物。 5-Formyl-5,6,7,8-tetrahydrofolic acid calcium salt 5-HCO-H4PteGlu Calcium folinate Hydrate Citrovorum factor calcium salt Leucovorin calcium salt
Product order:
Name Specifications Packing Price Delivery
Folinic acid calcium salt hydrate 98% 5g RMB 1155 Consulting service
Folinic acid calcium salt hydrate 98% 1g RMB 404.8 Consulting service
Quality Standard:
 
   纯度Purity                  ≥98.0% (HPLC)
水分Water                   ≤16.0 %
Storage:

用途  亚叶酸钙抵消叶酸拮抗剂的效果,叶酸拮抗剂是靠结合叶酸脱氢还原酶(dihydrofolate reductase),从而阻止叶酸转换成四氢叶酸。医学上,在甲氨喋呤化疗后,亚叶酸钙用于减少甲氨喋呤的毒性。亚叶酸钙也在抗癌方面增强5-氟尿嘧啶的细胞毒性效果。
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